2010 Research in tissue engineering for cell regeneration

Anseth is developing photopolymers that will change from soft to hard in response to cues such as ultraviolet light, and then degrade predictably over time. Such materials could be used to for orthopedic repairs, functioning as a replacement for damaged areas of bone and then slowly being replaced by regrowth of natural material as the body heals. Her pioneering approach applies photopolymerization and photodegradation to enable precise control in space and time of hydrogels' structure and composition. This research involves fundamental investigations into the molecular dynamics of processes at the cell-biomaterial interface.

Amplified Photodegradation of hydrogels & methods of producing the same; Degradable thiol-ene polymers; Synthesis & assembly of clickable microgels into cell-laden porous scaffolds; Covalently cross-linked hydrogels & methods of making & using same; Hydrogels & methods for producing & using the same; Semi-interpenetrating or interpenetrating polymer networks for drug delivery & tissue engineering; Preparation & use of photopolymerized microparticles; Process for the conversion of N.sub.20

Category:
Biology - Biological Engineering

Completion Status:
yes

Patent Number:
1100625;10189952;9631092;8859716;8703904;8519086;7625580;7288608;6864301;6403672;6224893;5314673

Co-Inventor:
Ian Marozas; Tobin Brown; Chrisstopher Bowman; Bilge Hacioglu; Charlie Huttelman; Ben Fairbanks; Brian Polizzotti; Cole DeForest; Robert S. Langer; Jennifer Elisseeff; Derek Sims; Theodore Randolph; Jennifer L. Owens; Corinne Lengsfeld; Theodore A Koch