RNA; COVID
Chemistry; RNA Technology
About This Innovation
Specializes in RNA-mediated mechanisms; developed in vitro-transcribed mRNA for protein therapies; with Drew Weissman invented the modified mRNA technology used in Pfizer-BioNTrch & Moderna's COVID-19 vaccines; co-discovered nucleoside modifications surpress the immunogenicity of RNA which has widened the therapuetic potential of mRNA in treating diseases; holds 16 patents
The Invention
RNA containing modified nucleosides & methods of use thereof; Purification & purity assessment of RNA molecules synthesized with modified nucleosides; RNA preparations comprising purified modified RNA for reprogramming cells; Methods for reducing immunogenicity of RNA
Key Information
Category:
Chemistry; RNA Technology
Completion Status:
yes
Patent Number:
8278036;11389547;11060107;11028370;10808242;10232055;10006007;9750824;9371511;9163213;9012219;8835108;8748089;8691966;AU2010328310Be; AU2018202479B2
Co-Inventor:
Drew Weissman; Gary Dahl; Anthony Person; Judith Meis; Jerome Jendrisak; Ugur Sakin
Patent Information
Patent Number: 8278036;11389547;11060107;11028370;10808242;10232055;10006007;9750824;9371511;9163213;9012219;8835108;8748089;8691966;AU2010328310Be; AU2018202479B2
Technical Specifications
RNA containing modified nucleosides & methods of use thereof; Purification & purity assessment of RNA molecules synthesized with modified nucleosides; RNA preparations comprising purified modified RNA for reprogramming cells; Methods for reducing immunogenicity of RNA
Collaboration
Co-Inventor: Drew Weissman; Gary Dahl; Anthony Person; Judith Meis; Jerome Jendrisak; Ugur Sakin
