1990 - Discovered BRCA1 & BRCA2 are genetic markers for breast & ovarian cancer.

Women's Health; Medical Diagnostics; Genetics

Status: yes

Patent: CA2217668C;5891857;WO99/22028;2218197;6177410;5821328;6512091;5622829;6197932;5985574;6149903

About This Innovation

* King was the first to show breast cancer can be inherited due to mutations in the gene she called BRCA1. * King's group demonstrated that a single gene on chromosome 17 could be linked to many breast and ovarian cancers. * 1996 with social worker Joan Marks and support from the Breast Cancer Research Foundation began the NY Breast Cancer Study which definitively determined the incidence of breast cancer & ovarian cancer was linked to inherited mutations of genes BRCA1 & BRCA2.

The Invention

Genetic markers for breast & ovarian cancer; Characterized BRCA1 & BRCA2 proteins & screening & therapeutic methods based on characterized BRCA1 & BRCA2 proteins; Modulators of Actin; Therapeutic methods for prostate cancer; Genetic markers for breast ovarian & prostate cancer

Key Information

Category:
Women's Health; Medical Diagnostics; Genetics

Completion Status:
yes

Patent Number:
CA2217668C;5891857;WO99/22028;2218197;6177410;5821328;6512091;5622829;6197932;5985574;6149903

Co-Inventor:
Lori Friedman; Beth Ostermeyer; Sarah Rowell; Eric Lynch; Csilla Szabo; Ming Lee; Jeffrey T. Holt; Roy A. Jensen; David L. Page; Thomas L. Jetton; Cheryl L. Robinson-Benion; Marilyn E. Thompson; Jan E. Morrow; Piri L. Welcsh; Pedro E. Leon; Mitchell S. Steiner;

Patent Information

Patent Number: CA2217668C;5891857;WO99/22028;2218197;6177410;5821328;6512091;5622829;6197932;5985574;6149903

Technical Specifications

Collaboration

Co-Inventor: Lori Friedman; Beth Ostermeyer; Sarah Rowell; Eric Lynch; Csilla Szabo; Ming Lee; Jeffrey T. Holt; Roy A. Jensen; David L. Page; Thomas L. Jetton; Cheryl L. Robinson-Benion; Marilyn E. Thompson; Jan E. Morrow; Piri L. Welcsh; Pedro E. Leon; Mitchell S. Steiner;