2022 - Nobel Prize in Chemistry for development of Bioorthogonal Chemistry and Click Chemistry

Bioorthogonal Chemistry, Click Chemistry
Status: yes
Patent: 11459398;11135299;11041850;10914742;10451632;10328161;10114026;10016498;9789180;9410958;9410966;9303068;9713966;8703936;8552100;8461298;8257932;8022040;7939626;7923582;7868152;7807619;7667012;7589182;7344703;7193034;6974580;6939945;6863895;6858213;6465612;5212075

About This Innovation

* Bertozzi coined the term bioorthogonal chemistry for chemical reactions compatible with living systems * Allows researchers to chemically modify molecules within living systems * Won Nobel Prize in chemistry 2022 * Also worked on Click Chemistry, describing how synthetic chemistry could emulate the way nature constructs complex molecules, using efficient reactions to join together simple, non-toxic building blocks * While at Berkeley, discovered viruses can bind to sugars in the body.

The Invention

Bioorthogonal Chemistry; modifying molecules;for a complete list of 32 patents see Doc Links

Key Information

Category:
Bioorthogonal Chemistry, Click Chemistry

Completion Status:
yes

Patent Number:
11459398;11135299;11041850;10914742;10451632;10328161;10114026;10016498;9789180;9410958;9410966;9303068;9713966;8703936;8552100;8461298;8257932;8022040;7939626;7923582;7868152;7807619;7667012;7589182;7344703;7193034;6974580;6939945;6863895;6858213;6465612;5212075

Co-Inventor:
Elliot C. Woods; Han Xiao; Melissa Gray; Peter V Robinson; Cheng-ting Tsai; Christina Woo; Christopher J. Chang; Genevieve C. van de Bittner; Elena A. Dubikovskaya; Mary Sloan Siegrist Palmore; John C. Jewett; Chelsea G. Gordon; Peyton Shieh; Brian P. Smart; Austin A. Pitcher; Krishnan K. Palaniappan; Mark A. Bredenback; Ellen May Sletten; Jie Song; Eduardo Saiz; Antoni P. Tomsia; Nicholas J. Agard; Jennifer A. Prescher; Jeremy Michael Baskin; Xing Chen; Alexander K. Zetti; Seung-Wuk Lee; Elena Saxon; John Kehoe; Andrew M. Bradbury; Spencer J. Williams; Joseph D. Mougous; Lisa A. Marcaurelle; Elena C. Rodriguez; Mark D. Bednarski; Jon O. Nagy

Patent Information

Patent Number: 11459398;11135299;11041850;10914742;10451632;10328161;10114026;10016498;9789180;9410958;9410966;9303068;9713966;8703936;8552100;8461298;8257932;8022040;7939626;7923582;7868152;7807619;7667012;7589182;7344703;7193034;6974580;6939945;6863895;6858213;6465612;5212075

Technical Specifications

Bioorthogonal Chemistry; modifying molecules;for a complete list of 32 patents see Doc Links

Collaboration

Co-Inventor: Elliot C. Woods; Han Xiao; Melissa Gray; Peter V Robinson; Cheng-ting Tsai; Christina Woo; Christopher J. Chang; Genevieve C. van de Bittner; Elena A. Dubikovskaya; Mary Sloan Siegrist Palmore; John C. Jewett; Chelsea G. Gordon; Peyton Shieh; Brian P. Smart; Austin A. Pitcher; Krishnan K. Palaniappan; Mark A. Bredenback; Ellen May Sletten; Jie Song; Eduardo Saiz; Antoni P. Tomsia; Nicholas J. Agard; Jennifer A. Prescher; Jeremy Michael Baskin; Xing Chen; Alexander K. Zetti; Seung-Wuk Lee; Elena Saxon; John Kehoe; Andrew M. Bradbury; Spencer J. Williams; Joseph D. Mougous; Lisa A. Marcaurelle; Elena C. Rodriguez; Mark D. Bednarski; Jon O. Nagy