1995 - Development of the compound cilastatin sodium, an inhibitor of renal dehydropeptidase.

Organic Chemistry
Status: yes
Patent: 4406902; 4290966; 4094976

About This Innovation

* Brown worked to develop the compound cilastatin sodium * This led to the creation of Primaxin, an antibiotic used to treat severe internal infections, diseases caused by flesh-eating bacteria, & some types of pneumonia * Spent 36 years in research before switching to a career as an educator * Has written 2 books profiling African-American women in chemistry.

The Invention

Dipeptidase inhibitors; Process for the preparation of traumatin; Anticoccidial cyclicamino ethanols & esters thereof

Key Information

Category:
Organic Chemistry

Completion Status:
yes

Patent Number:
4406902; 4290966; 4094976

Co-Inventor:
Wallace T. Ashton; Louis Barash; Donald W. Graham; Edward F. Rogers; Richard A. Dybas

Patent Information

Patent Number: 4406902; 4290966; 4094976

Technical Specifications

Dipeptidase inhibitors; Process for the preparation of traumatin; Anticoccidial cyclicamino ethanols & esters thereof

Collaboration

Co-Inventor: Wallace T. Ashton; Louis Barash; Donald W. Graham; Edward F. Rogers; Richard A. Dybas