1995 - Development of the compound cilastatin sodium, an inhibitor of renal dehydropeptidase.
Organic Chemistry
About This Innovation
* Brown worked to develop the compound cilastatin sodium * This led to the creation of Primaxin, an antibiotic used to treat severe internal infections, diseases caused by flesh-eating bacteria, & some types of pneumonia * Spent 36 years in research before switching to a career as an educator * Has written 2 books profiling African-American women in chemistry.
The Invention
Dipeptidase inhibitors; Process for the preparation of traumatin; Anticoccidial cyclicamino ethanols & esters thereof
Key Information
Category:
Organic Chemistry
Completion Status:
yes
Patent Number:
4406902; 4290966; 4094976
Co-Inventor:
Wallace T. Ashton; Louis Barash; Donald W. Graham; Edward F. Rogers; Richard A. Dybas
Patent Information
Patent Number: 4406902; 4290966; 4094976
Technical Specifications
Dipeptidase inhibitors; Process for the preparation of traumatin; Anticoccidial cyclicamino ethanols & esters thereof
Collaboration
Co-Inventor: Wallace T. Ashton; Louis Barash; Donald W. Graham; Edward F. Rogers; Richard A. Dybas