1948 - Production of dextran as plasma substitute used by medical personal in the Korean and Vietnam wars.

Hematology
Status: yes
Patent: 2587623; 3000790; 3096293; 3054689; 3021323; 2961378; 2742399; 2673828; 2231787; 2231788

About This Innovation

* Jeanes’ research led to the isolation of dextran-producing bacteria, providing for development of a mass production process * Dextran used in a dextran-based blood plasma extender, keeping someone who had lost a great deal of blood alive longer. * Used by medical personal in the Korean and Vietnam wars to treat injured soldiers. * Jeanes was the first woman to receive the Distinguished Service Award given by the Department of Agriculture in 1953.

The Invention

Acylation of Dextran in formamide; Methode of producing an atypically salt-responsive alkali-deacetylated polysaccaride; Method of increasing the viscosity of an aqueous solution of a deacetylated polysaccaride; Atypically salt-responsive alkali-deacetylated polysaccardie produced by xanthomonas campestris; Phosphomannan NRRL Y-2448; Method of producing phosphomannan by saccaride fermentation; Production of Dextranase; Preparation & use of polysaccaride producing enzyme; Phenanthrene dicarboxylic acid; 9-aroyl-10-phenanthroic acid

Key Information

Category:
Hematology

Completion Status:
yes

Patent Number:
2587623; 3000790; 3096293; 3054689; 3021323; 2961378; 2742399; 2673828; 2231787; 2231788

Co-Inventor:
James H Sloneker; Robert G. Benedict; Lynferd J. Wickerham; S. Peter Rogovin; Henry M. Tsuchiya; Helen M. Bricker; Carl A. Wilham; Harold J. Koepsell; Anna Kazenko; Eugene S. Sharpe; Roger Adams

Patent Information

Patent Number: 2587623; 3000790; 3096293; 3054689; 3021323; 2961378; 2742399; 2673828; 2231787; 2231788

Technical Specifications

Acylation of Dextran in formamide; Methode of producing an atypically salt-responsive alkali-deacetylated polysaccaride; Method of increasing the viscosity of an aqueous solution of a deacetylated polysaccaride; Atypically salt-responsive alkali-deacetylated polysaccardie produced by xanthomonas campestris; Phosphomannan NRRL Y-2448; Method of producing phosphomannan by saccaride fermentation; Production of Dextranase; Preparation & use of polysaccaride producing enzyme; Phenanthrene dicarboxylic acid; 9-aroyl-10-phenanthroic acid

Collaboration

Co-Inventor: James H Sloneker; Robert G. Benedict; Lynferd J. Wickerham; S. Peter Rogovin; Henry M. Tsuchiya; Helen M. Bricker; Carl A. Wilham; Harold J. Koepsell; Anna Kazenko; Eugene S. Sharpe; Roger Adams

Women Behind This Innovation