2000 - Bioengineering to develop new technologies to provide health care to vulnerable populations.

Medical Devices; Medical Diagnostics
Status: done
Patent: 7365844; 10314990;7499161; 7492535; 7236815; 6766184; 6697666; 6639674; 6370422; 6258576; 6241662; 6187289; 6135965; 6095982; 5991653; 5929985; 5920399; 5842995; 5699795; 5697373; 5612540; 5562100; 6571118; 5421339; 5623932; EP 1267709B1; EP0449883B1; EP0957744B1; CA 2215207C

About This Innovation

* Richards-Kortum founded Rice360 Institute for Global Health to develop highly effective, low-cost healthcare solutions for underserved communities * Works to educate future leaders to innovate and implement solutions for underserved healthcare options * Developed a low-cost, battery imaging system that could detect premalignant tissue without a biopsy * Her lab works to advance nanotech & molecular imaging in order to develop portable & inexpensive optical imaging systems * Developed low-power devices for premature babies in impoverished areas at low-cost. low-cost battery imaging system to detect premalignant tissues without a biopsy; works to advance nanotech & molecular imaging to develop portable & inexpensive optical imaging systems; developed Pumani CPAP system to help newborns with breathing problems; developed BiliSpec a diagnostic tool for jaundice & DoseRight a solution for precise administration of liquid medicine to children; teaches students to be technological innovators who think in human terms

The Invention

Vision enhancement system for improved detection of epithelial neoplasia & other conditions; Bubble continuous positive airway pressure; Depth-resolved spectroscopy method & application; Multimodal miniature microscope; Method for probabilistically classifying tissue in vitro & in vivo using fluorescence spectroscopy; Methods & applications for diagnostic multispectral digital imaging; Applications for the characterization of tissue of epithelial lined viscus; Methods & applications for polarized reflectance spectroscopy; fiber-optic confocal imaging application & methods of use; Diagnostic method & application for cervical squamous intraepithelial lesions in vitro & in vivo using fluorescence spectroscopy; Acetic Acid as a signal enhancing contrast agent in fluorescence spectroscopy; Ascetic acid as a contrast in reflectance confocal imaging of tissue; Spectroscopic detection of cervical pre-cancer using radial basis function networks; spectroscopic method & application for optically detecting abnormal mammalian epithelial tissue; Near-infrared raman spectroscopy for in vitro & in Vivo detection of cervical pre-cancers; Multispectral imaging probe; Multispectral imaging method & application; Spectroscopic probe for in vivo measurement of raman signals; Optical probe for the detection of cervical neoplasia using fluorescence spectroscopy & application incorporating smae; Optical method & application for the diagnosis of cervical pre-cancer using raman & fluorescence spectroscopies; Optical method for the detection of cervical neoplasia using fluorescence spectroscopy; Method for laser induced fluorescence of tissue; spectral diagnosis of diseased tissue; Contour mapping of spectral diagnostics; Method & application for dose measurement; Enhancing contrast in biological imaging; Paper based spectrophotometric detection of blood hemoglobin concentration; Combined fluorescence & reflectance spectroscopy; Diagnosis of dysplasia using laser induced fluorescence; Probe for the detection of cervical neoplasia using fluorescence spectroscopy

Key Information

Category:
Medical Devices; Medical Diagnostics

Completion Status:
done

Patent Number:
7365844; 10314990;7499161; 7492535; 7236815; 6766184; 6697666; 6639674; 6370422; 6258576; 6241662; 6187289; 6135965; 6095982; 5991653; 5929985; 5920399; 5842995; 5699795; 5697373; 5612540; 5562100; 6571118; 5421339; 5623932; EP 1267709B1; EP0449883B1; EP0957744B1; CA 2215207C

Co-Inventor:
Urs Utzinger; Ekaterina S. Svistisn; Z. Maria Oden; Jocelyn Kaye Brown; Robert H.J. Miros; Elizabeth Molyneux; Richard A. Schwarz; Ann M. Gillenwater; Nirmala Ramanujam; Anita Makadevan-Jansen; Michele Follen (later Mitchell); Calum MacAuldy; Konstantin Sokolov; Rebekah Drezek; Colin L. Smithpeter; Brett S. Bowman; Michael R. Descour; Anant Agrawal; Costas Pitris; Carrie Brookner; Andres F. Zuluaga; Kagan Tumer; Joydeep Ghosh; David R. Sandison; Mark R. Platzbecker; David L. Armour; Marcus J. Craig; Timothy D. Vargo; Randal R. Lockhart; Gregg Staerkel; Youseph Yazdi; Carter Kittrell; Robert M. Cothren; Michael S. Feld; JosephJ. Baraga; Kyungwon An; Richard P. Rawa; Young D. Park; Anand V. Mehta; Paola Taroni; Lucene Tong; Ramachandra R. Dasari; Julia Ellen Davidson Lukomnik; cindy M. Dink; amanda Michelle Guiterrez; Carlos Amaro; Tom collier; Joseph S. Yan; Meaghan McNeill Bond; John Neil Wright; Carlos Elguea; Anthony J. Durkin; Holger Fuchs; Douglas L. Heintzelman; Sharon Thomsen

Patent Information

Patent Number: 7365844; 10314990;7499161; 7492535; 7236815; 6766184; 6697666; 6639674; 6370422; 6258576; 6241662; 6187289; 6135965; 6095982; 5991653; 5929985; 5920399; 5842995; 5699795; 5697373; 5612540; 5562100; 6571118; 5421339; 5623932; EP 1267709B1; EP0449883B1; EP0957744B1; CA 2215207C

Technical Specifications

Vision enhancement system for improved detection of epithelial neoplasia & other conditions; Bubble continuous positive airway pressure; Depth-resolved spectroscopy method & application; Multimodal miniature microscope; Method for probabilistically classifying tissue in vitro & in vivo using fluorescence spectroscopy; Methods & applications for diagnostic multispectral digital imaging; Applications for the characterization of tissue of epithelial lined viscus; Methods & applications for polarized reflectance spectroscopy; fiber-optic confocal imaging application & methods of use; Diagnostic method & application for cervical squamous intraepithelial lesions in vitro & in vivo using fluorescence spectroscopy; Acetic Acid as a signal enhancing contrast agent in fluorescence spectroscopy; Ascetic acid as a contrast in reflectance confocal imaging of tissue; Spectroscopic detection of cervical pre-cancer using radial basis function networks; spectroscopic method & application for optically detecting abnormal mammalian epithelial tissue; Near-infrared raman spectroscopy for in vitro & in Vivo detection of cervical pre-cancers; Multispectral imaging probe; Multispectral imaging method & application; Spectroscopic probe for in vivo measurement of raman signals; Optical probe for the detection of cervical neoplasia using fluorescence spectroscopy & application incorporating smae; Optical method & application for the diagnosis of cervical pre-cancer using raman & fluorescence spectroscopies; Optical method for the detection of cervical neoplasia using fluorescence spectroscopy; Method for laser induced fluorescence of tissue; spectral diagnosis of diseased tissue; Contour mapping of spectral diagnostics; Method & application for dose measurement; Enhancing contrast in biological imaging; Paper based spectrophotometric detection of blood hemoglobin concentration; Combined fluorescence & reflectance spectroscopy; Diagnosis of dysplasia using laser induced fluorescence; Probe for the detection of cervical neoplasia using fluorescence spectroscopy

Collaboration

Co-Inventor: Urs Utzinger; Ekaterina S. Svistisn; Z. Maria Oden; Jocelyn Kaye Brown; Robert H.J. Miros; Elizabeth Molyneux; Richard A. Schwarz; Ann M. Gillenwater; Nirmala Ramanujam; Anita Makadevan-Jansen; Michele Follen (later Mitchell); Calum MacAuldy; Konstantin Sokolov; Rebekah Drezek; Colin L. Smithpeter; Brett S. Bowman; Michael R. Descour; Anant Agrawal; Costas Pitris; Carrie Brookner; Andres F. Zuluaga; Kagan Tumer; Joydeep Ghosh; David R. Sandison; Mark R. Platzbecker; David L. Armour; Marcus J. Craig; Timothy D. Vargo; Randal R. Lockhart; Gregg Staerkel; Youseph Yazdi; Carter Kittrell; Robert M. Cothren; Michael S. Feld; JosephJ. Baraga; Kyungwon An; Richard P. Rawa; Young D. Park; Anand V. Mehta; Paola Taroni; Lucene Tong; Ramachandra R. Dasari; Julia Ellen Davidson Lukomnik; cindy M. Dink; amanda Michelle Guiterrez; Carlos Amaro; Tom collier; Joseph S. Yan; Meaghan McNeill Bond; John Neil Wright; Carlos Elguea; Anthony J. Durkin; Holger Fuchs; Douglas L. Heintzelman; Sharon Thomsen