Immunology

with Irv Weissman discovered CD24 proteins role is to "signal" cancer cells from "being eaten" by macrophages (white blood cells); leader in the field of innate immunity in cancer & conducts research aimed at understanding the regulators of intratumoral macrophage function; Pheast Therapeutics (company she co-founded) aims to bolster innate immune responses to cancer by blocking the signal that certain cancer cells send to ward off the bodys immune system ; her research targets ovarian & breast cancers

2 patents pending: 1)Analysis of polymorphisms in sirp-alpha for evaluating response to immunotherapy; 2) Compositions & methods for inducing phagocytosis

Category:
Cancer Research

Completion Status:
yes

Patent Number:
Pending

Co-Inventor:
Ying Ying Yiu; Michal Caspi Tal; Hanna Maria Ollila; Irving L. Weissman