Co-founded SpherIngenics, using microbead technology addresses complex, infected wounds

Boyen founded Spheringenics, Inc. together with Zvi Schwartz. It is a cell-based therapies company, using delivery of copper oxide microparticles to stimulate cell repair in infected wounds. She is also Director & CSO; co-founder & CSO of Orthonics a company that makes medical devices; 1993 co-founder & CEO of OsteoBiologics Inc a company that makes tissue engineered medical products; co-founder & CEO of Biomedical Development corporation a company that makes innovations in medical technologies; 2023 co-founder, CEO & CSO of Pascal Medical Corporation; her developments include novel technology for controlling nanotexture on metal & polymer surfaces to study cell responses for regenerative medical applications, elucidating the mechanisms used by steroid hormones like vitamin D & estrogen & microRNAs in the regulation of bone & cartilage cells

Polymer hydrogels for in vivo applications & methods for using & preparing same; Protein delivery from stem cell microcarriers; Surface modification of implant devices; Cranial suture snake algorithm; Hydrogel implant with superficial pores; Articular joint implant; Biomolecular coating for implants; Method of making load bearing hydrogel implants; Microencapsulation of cells in hydrogels using electrostatic potentials; Method of treating joints with hydrogel implants; Surface directed cellular attachment; Load bearing biocompatible device; Method of making hydrogel implants; Calcium binding proteolipid compositions & methods; Continuous release polymeric implant carrier; Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor; Methods & compositions for calcium binding proteolipid encoding nucleic acids; Biodegradable implant material comprising bioactive ceramics; Biodegradable implant; Activation of latent transforming growth factor beta by matrix vesicles; Multi=phase bioerodible implant/carrier & method of manufacturing & using same; Biodegradable implant for fracture nonunions; Resorbable materials based on independently gelling polymers of a single enantiomeric lactide; Process of making a resorbable implantation device

Category:
Engineering, Biomedical

Completion Status:
yes

Patent Number:
11707526; 11253597; 10441610; 10039831; 9889229; 9135713; 8895073; 8486436; 8445006; 8318192; 8202701; 8142808; 8114431; 8002830; 7910124; 7682540; 6444446; 6013853; 6001352; 5989907; 5977204; 5876452; 5656450; 5607474; 5492697; 5397572; 5290494

Co-Inventor:
Niren Murthy; Christopher Hermann; David Scott Wilson; Xianghai Ning; Zvi Schwartz; Robert Goldberg; Tamin Diab; Christopher S.D. Lee; Shirae Kerisha Leslie; Ramsey C. Kinney; Rolando A. Gittens Ibacache; Jonathan Vernon; Kenneth H. Sandhage; Robert E. Guldberg; Stephen J. Kennedy; David N. Ku; Andres J. Garcia; Catherine D. Reyes; Timothy Petrie; Jenny E. Raynor; David M. Collard; Abigail M. Wojtowicz; Simon Van Dijk'; D. D. Dean; Kyriacos A. Athanasiou; Gabriele Niederauer; Kristine Kieswetter; Neil C. Leatherburg; David C. Greenspan; Lynda F. Bonewald; Chandra M. Agrawal; James D. Heckman; Allan G. A. Coombes